Dr. Cheatle is an Associate Professor of Psychiatry and Anesthesiology and Critical Care at the Perelman School of Medicine, University of Pennsylvania. He directs the Pain and Chemical Dependency Research Program within the Center for Studies of Addiction and serves as Director of Behavioral Medicine in the PENN Anesthesia Pain Medicine Center. He has more than three decades experience in the treatment of complex chronic pain conditions, with a particular focus on research and treatment of opioid use disorders in patients with chronic pain, improving pain care and reducing risk of suicide in patients with pain and substance use disorders. He was the PI of a recently completed RO1 NIDA grant on clinical and genetic characteristics of opioid addiction in chronic pain; a project PI of a NIDA P-60 Center grant on a longitudinal study of the development of addiction in patients initiating prescription opioid therapy for chronic pain in primary care. Currently he is a co-investigator of a recently funded NIH R01 examining the role of opioid adherence profiles in cancer pain self – management and outcomes; co-I in a R21 evaluating the effect of CBD in reducing pain and opioid use in patients with chronic lumbar radiculopathy; co-investigator of the HOPE Consortium to Reduce Pain and Opioid Use in patients on Hemodialysis; and PI of a recently funded NIH R21 examining the effect of cognitive behavioral therapy delivered preoperatively to patients undergoing total knee arthroplasties in reducing post-operative pain, opioid use and the chronification of pain.